How PalindromX technology works
Capture antibodies are used in conventional formats: detector antibodies are labelled with a small, carefully structured DNA molecule. After formation of the antibody-protein-antibody complex, a large complementary DNA molecule is added and this engages with the detector antibody-bound DNA. The structure of this larger DNA molecule allows it to be amplified by specific probes, giving rise to a signal, which is measured. This approach massively reduces non-specific amplification of DNA that is inevitably present in the analytical sample and causes problems with conventional immuno-PCR detection systems.
